Publications

Evaluating key characteristics of ideal colorectal cancer screening modalities: the microsimulation approach

A Deibel, L Deng, CY Cheng, M Schlander, T Ran, B Lang, N Krupka, N Beerenwinkel, G Rogler, R Wiest, A Sonnenberg, J Poleszczuk, B Misselwitz. 

Gastrointestinal Endoscopy, VOLUME 94, ISSUE 2, P379-390.E7, AUGUST 01, 2021

Comparative effectiveness and cost-effectiveness analysis of a urine metabolomics test vs. alternative colorectal cancer screening strategies
S Barichello, L Deng, K Ismond, D Loomes, EK Kirwin, H Wang, D Chang, LW Svenson, NX Thanh
International Journal of Colorectal Disease, November 1. 2019, 0179-1958

Urinary Metabolomics to Identifty a Unique Biomarker Panel for Detecting Colorectal Cancer: A Multicenter Study
L Deng, K Ismond, Z Liu, J Constable, H Wang, OI Alatise, MR Weiser, TP Kingham, D Chang
Cancer Epidemiology, Biomarkers & Prevention, August, 2019, 10.1158/1055-9965.EPI-18-1291

Development and Validation of a High-Throughput Mass Spectometry Based Urine Metabolomic Test for the Detection of Colonic Adenomatous Polyps
L Deng, D Chang, RR Foshaug, R Eisner, VK Tso, DS Wishart, RN Fedorak
Metabolites, June 22, 2017, 7(3), 32 

Clinical validation of a novel urine-based metabolomic test for the detection of colonic polyps on Chinese population
L Deng, H Fang, V Tso, Y Sun, RR Foshaug, SC Krahn, F Zhang, Y Yan, H Xu, D Chang, Y Zhang, RN Fedorak
International Journal of Colorectal Disease:Available Online, 2016 Dec 01

Consistency of Metabolite Determination from NMR Spectra over Time and Between Operators
V Tso, R Eisner, S Macleod, KP Ismond, RR Foshaug, H Wang, R Joseph, D Chang, N Taylor, RN Fedorak
Metabolomics: Open Access, 2015 Sept; 5(3):151

Budgeted transcript discovery: a framework for joint exploration and validation studies
S Khan, R Greiner
Bioinformatics and Biomedicine, 2014 IEEE International Conference Nov;188-91

Urine-based test for detection of colonic polyps: the coming of age
H Wang, R Eisner, RN Fedorak
Colorectal Cancer, 2014 Jun;3(3):239-41

Development and validation of a highly sensitive urine-based test to identify patients with colonic adenomatous polyps
H Wang, V Tso, C Wong, D Sadowski, RN Fedorak
Clinical and Translational Gastroenterology, 2014 Mar;5:e54

A machine-learned predictor of colonic polyps based on urinary metabolomics
R Eisner, R Greiner, V Tso, H Wang, RN Fedorak
Biomed Research International 2013 Nov;2013:303982

Metabolomic profiles are gender, disease and time specific in the interleukin-10 gene-deficient mouse model of inflammatory bowel disease
VK Tso, BC Sydora, RR Foshaug, TA Churchill, J Doyle, CM Slupsky, RN Fedorak
PLoS ONE,2013 Jul;8(7):e67654

Patients undergoing colorectal cancer screening underestimate their cancer risk and delay presentation for screening
H Wang, N Gies, C Wong, D Sadowski, B Moysey, RN Fedorak
Canadian Journal of Gastroenterology, 2012 Jul;26(7):419-23

The sensitivity and specificity of guaiac and immunochemical fecal occult blood tests for the detection of advanced colonic adenomas and cancer
CK Wong, RN Fedorak, CI Prosser, ME Stewart, S Veldhuyzen van Zanten, DC Sadowski
International Journal of Colorectal Disease, 2012 Dec;27(12):1657-64

Metabolomics and detection of colorectal cancer in humans - a systematic review
H Wang, V Tso, C Slupsky, RN Fedorak
Future Oncology, 2010 Sep;6(9):1395-1406