Metabolomics is an emerging field of "omics" research specializing in the near global analysis of small molecule metabolites found in living organisms. Metabolomics is a powerful approach because metabolites and their concentrations, unlike other "omics" measures, directly reflect the underlying biochemical activity and state of cells / tissues. Thus metabolomics best represents the molecular phenotype. 

Clinical Metabolomics

Metabolomic disturbances have been associated with many human diseases, including cancer, diabetes, and cardiovascular disease. Metabolomics provides a link between metabolic pathways and the upstream genome that governs them. With the advances in analytical technologies, metabolomics is becoming a powerful tool for identifying diagnostic biomarkers of diseases, elucidating the pathological mechanisms, discovering novel drug targets, predicting drug responses, interpreting the mechanisms of drug action, as well as enabling precision treatment of patients.